Two-sample tests for comparing proportions
نویسندگان
چکیده
منابع مشابه
Sample Size Calculation for Comparing Proportions
In clinical research, in addition to continuous responses, primary clinical endpoints for assessment of efficacy and safety of a drug product under investigation could be binary responses. For example, in cancer trials, patients’ clinical reaction to the treatment is often classified as response (e.g., complete response or partial response) or nonresponse. Based on these binary responses, the p...
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An equivalence test example will set the stage for the discussion of the terminology that follows. Suppose that the response rate of the standard treatment of a disease is 0.70. Unfortunately, this treatment is expensive and occasionally exhibits serious side-effects. A promising new treatment has been developed to the point where it can be tested. One of the first questions that must be answer...
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To fix these ideas, consider the following fictitious data concerning the relationship between smoking and lung cancer. Suppose that a sample of N = 100 cases of identical twins in which only one twin has lung cancer is selected for further study. The twin with lung cancer is the case. The other twin serves as the control. Each pair of twins is surveyed to determine if they smoke tobacco. The r...
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A non-inferiority test example will set the stage for the discussion of the terminology that follows. Suppose that the current treatment for a disease works 70% of the time. Unfortunately, this treatment is expensive and occasionally exhibits serious side-effects. A promising new treatment has been developed to the point where it can be tested. One of the first questions that must be answered i...
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Background and purpose: Sample size and its determination is one of the most important problems in health researches. Calculating sample size for prevalence studies is one of the common questions of sample size topics. Minimum sample size with least complexity is desirable in order to achieve the basic goal of these studies. This study aims to compare two formulas of sample size calculation for...
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ژورنال
عنوان ژورنال: Drug Delivery System
سال: 2015
ISSN: 0913-5006,1881-2732
DOI: 10.2745/dds.30.235